The application of three-photon excitation to biomedical imaging is demonstrated by combining the three-photon excitation properties of ZnS nanocrystals and the visible emission from Mn2+ dopants. The biocompatible, doped nanocrystals are used for high-resolution cellular imaging and in vivo tumour-targeting imaging under non-invasive conditions.
- Jung Ho Yu
- Seung-Hae Kwon
- Taeghwan Hyeon