Search

Unlike some planets, the Venusian polar vortex is warmer than the mid-latitudes at cloud-top level, but the mechanism behind this is unknown. Here, the authors use a general circulation model and suggest the cold collar and warm polar regions are due to residual mean meridional circulation intensified by thermal tides.

A genome-wide association study highlights a variant in DOCK2, which is common in East Asian populations but rare in Europeans, as a host genetic risk factor for severe COVID-19.

Genetic mechanisms influencing COVID-19 susceptibility are not well understood. Here, the authors analyzed whole blood RNA-seq data of 465 Japanese individuals with COVID-19, highlighting thousands of fine-mapped variants affecting expression and splicing of genes, as well as the presence of COVID-19 severity-interaction eQTLs.

Analysis of the blood DNA virome in patients with COVID-19 and autoimmune disease associates endogenous HHV-6 (eHHV-6) and high anellovirus load with increased disease risk, most notably for systemic lupus erythematosus. eHHV-6 carriers show a distinct immune response.

Future quantum communication technologies require entanglement between stationary and flying qubits, in systems that are inherently scalable. To this end, De Greveet al.present full state tomography of a qubit pair formed by entangling a quantum dot spin and a photon, with a fidelity of over 90%.

The structures of inorganic clusters are commonly characterized by mass spectrometry (MS), but neutral sulfur clusters heavily fragment under MS conditions, preventing their exact mass determination. Here, the authors successfully perform MS on labile cyclic sulfur clusters by stabilizing them within ionic supramolecular capsules.

More than 10,000 time-division-multiplexed degenerate parametric oscillators are generated using phase-sensitive amplification in a nonlinear optical fibre. They can be used to simulate a coherent Ising machine that could solve difficult computing problems.

Peripheral blood mononuclear cells from 73 Japanese patients with coronavirus disease 2019 (COVID-19) and 75 healthy controls were analyzed using single-cell transcriptomics. Combining these data with genotyping data highlights the interplay between host genetics and the immune response in modulating disease severity.

An ultrafast, all-optical spin echo technique is used to increase the decoherence time of a single quantum dot electron spin from nanoseconds to several microseconds. The ratio of decoherence time to gate time exceeds 10⁵, suggesting strong promise for future photonic quantum information processors and repeater networks.

A technique that controls electron spins using single optical pulses far detuned from the optical transition has been demonstrated. This approach may enable fast spin manipulation in a variety of solid-state systems.

Bound pairs consisting of a vortex and an antivortex are expected to dominate the low-temperature physics in a variety of two-dimensional systems. The observation of such bound pairs, however, remains elusive. A study now establishes non-equilibrium condensates of exciton-polaritons as a platform for exploring the physics of vortex–antivortex pairs.

Conventional quantum cryptography relies on monitoring signal disturbance to make sure that information leakage is negligible; here a new quantum method of achieving security is described, in which little information is leaked to the eavesdropper regardless of the signal disturbance.

An electrically pumped polariton laser is constructed using a quantum well microcavity, and its polaritonic nature is demonstrated unambiguously by using a magnetic field to probe the part-light, part-matter character of the system.

Similar to atoms in cold gases, exciton–polaritons in semiconductor microcavities can undergo Bose–Einstein condensation. Now, formation of a condensate in an excited orbital state has been observed in such a system, underlining the potential of exciton–polariton condensates to emulate condensed-matter physics.

A network of four degenerate optical parametric oscillators (OPOs) is employed to find the ground state of the Ising Hamiltonian. The good performance of the network reveals the potential of OPOs for many similar problems.

In many ways, semiconductor quantum dots behave like natural atoms, but it has proved difficult to manipulate them using resonant laser light. That problem is now overcome.

Autophagic activity decreases with age via unknown mechanisms. Here the authors show that expression of the negative autophagy regulator Rubicon increases with age, that its genetic ablation improves lifespan and ameliorates a number of age-associated phenotypes in invertebrates and in mouse models.

Quantum communication requires quantum correlations between the information processing units and the information carrying units. Here, the authors use time-bin encoding and frequency downconversion to telecom wavelengths to achieve kilometre-scale spin-photon correlations.

Although exciton–polariton lasers have been experimentally demonstrated in a variety of material systems, robust practical implementations are still challenging. Similarities with atomic Bose–Einstein condensates make the system suitable for chip-based quantum simulators for non-trivial many-body physics.

Diabetes is a major cause of kidney disease. Here Kikuchi et al. show that phenol sulfate, a gut microbiota-derived metabolite, is increased in diabetic kidney disease and contributes to the pathology by promoting kidney injury, suggesting phenyl sulfate could be used a marker and therapeutic target for the treatment of diabetic kidney disease.

Electron spin in quantum dots are extensively studied as a qubit for quantum information processing. However, the coherence of electron spin is deleteriously influenced by nuclear spin. Quantum-dot holes are a potential alternative. Full control over hole-spin qubits is now achieved using picosecond lasers.

According to quantum mechanics, matter can be regarded as waves. ‘Matter waves’ made from composite particles known as polaritons, which are part light and part matter, can be amplified in a semiconductor to produce a matter-wave analogue of a laser amplifier.

Primary open-angle glaucoma (POAG) is highly heritable, yet not well understood from a genetic perspective. Here, the authors perform a meta-analysis of genome-wide association studies in 34,179 POAG cases, identifying 44 previously unreported risk loci and mapping effects across multiple ethnicities.

A total of 1074 patients with a history of ischemic stroke enrolled in The Recurrent Stroke Prevention Clinical Outcome (RESPECT) Study were assigned to intensive blood pressure (BP) control group (blood pressure < 120/80 mmHg) or standard blood pressure control group (blood pressure < 140/90 mmHg) and were followed up for a mean of 3.9 years. Seventy-eight first recurrent strokes occurred, including 70 ischemic stroke and 8 intracerebral hemorrhage. Intensive treatment did not change annual risk of ischemic stroke (1.74% vs. 1.75%, P = 0.999), but markedly reduced risk of hemorrhagic stroke (0.00% vs. 0.39%, P = 0.005). Beneficial effect of intensive BP control were observed for risk of hemorrhagic stroke in the patients with a history of ischemic stroke.

To use optical systems to do the same work as electronics, photons must be made to interact with one another — something that they are reluctant to do in ordinary materials. But a new type of non-linear optical cavity makes them interact so strongly that when one photon is trapped inside, no others can enter. This behaviour may eventually form the basis for devices in quantum computers.

Entanglement of the spin of an electron in a semiconductor quantum dot with a single photon is reported, and verified by means of time-resolved frequency downconversion to a telecommunications wavelength; this process is an essential requirement for future quantum networks.