Zhao and colleagues find that neuropathic pain is accompanied by an increase in the expression of an antisense long noncoding RNA (lncRNA) that downregulates Kcna2 currents and increases excitability in rat dorsal root ganglion neurons. Preventing the expression of the so-called Kcna2 antisense RNA mitigates neuropathic pain symptoms.
- Xiuli Zhao
- Zongxiang Tang
- Yuan-Xiang Tao
