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Signal Transduction and Targeted Therapy (2)
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Showing 1–10 of 10 results

Advanced filters: Author: Yueming Song Clear advanced filters

Human motor cortex encodes complex handwriting through a sequence of stable neural states

How does the brain encode complex movement sequences? Qi et al. reveal that the brain decomposes sequences into temporal states, each corresponding to a small movement fragment, with motor cortex neurons dynamically altering their encoding across states.

Yu Qi
Xinyun Zhu
Yueming Wang
ResearchOpen Access02 Apr 2025
Nature Human Behaviour

Volume: 9, P: 1260-1271
Cryo-EM structure of an activated GPR4–Gs signaling complex

The proton-sensing GPCRs detect extracellular low pH and regulate diverse physiological responses. Here, the authors report cryo-EM structures of GPR4, which provide insight into the structural features of proton sensing mechanism.

Yitong Ma
Yijie Wang
Gaojie Song
ResearchOpen Access11 Jan 2025
Nature Communications

Volume: 16, P: 1-10
Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls

The authors perform a genome-wide association study of adolescent idiopathic scoliosis patients of Han Chinese descent, and identify 3 new loci for disease susceptibility.

Zezhang Zhu
Nelson Leung-Sang Tang
Jack Chun-Yiu Cheng
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-6
Structural basis of CXC chemokine receptor 2 activation and signalling

Structures of the G_i-coupled CXC chemokine receptor 2 (CXCR2) in complex with CXCL8 and in complex with an allosteric antagonist provide insight into the ligand binding and activation of CXCR2 and its mode of G-protein coupling.

Kaiwen Liu
Lijie Wu
Zhi-Jie Liu
Research01 Jul 2020
Nature

Volume: 585, P: 135-140
Anti-PD-L1 antibody ASC22 in combination with a histone deacetylase inhibitor chidamide as a “shock and kill” strategy for ART-free virological control: a phase II single-arm study

Luling Wu
Zhihang Zheng
Jun Chen
ResearchOpen Access09 Sept 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-11
Meglumine cyclic adenylate improves cardiovascular hemodynamics and motor-function in a rat model of acute T4 thoracic spinal cord injury

Yueming Song
Limin Guo
Jingwu Liao
Research04 Jul 2023
Spinal Cord

Volume: 61, P: 422-429
Efficient and stable emission of warm-white light from lead-free halide double perovskites

After alloying with metal cations, a lead-free halide double perovskite shows stable performance and remarkably efficient white-light emission, with possible applications in lighting and display technologies.

Jiajun Luo
Xiaoming Wang
Jiang Tang
Research07 Nov 2018
Nature

Volume: 563, P: 541-545
SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity

Chunlin Zuo
Lijun Wang
Wentian Yang
ResearchOpen Access06 Apr 2018
Bone Research

Volume: 6, P: 1-13
Butyrate upregulates endogenous host defense peptides to enhance disease resistance in piglets via histone deacetylase inhibition

Haitao Xiong
Bingxiu Guo
Huahua Du
ResearchOpen Access27 May 2016
Scientific Reports

Volume: 6, P: 1-12
TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases

Miao Zhang
Yueming Ma
Bing Wang
ReviewsOpen Access05 Jul 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-38