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Electrolyzers operating efficiently at industrial current densities offer promise but face challenges for practical NO_x⁻ -to-ammonia conversion. Here, the authors report a full runner electrolyzer stack that enhances mass transfer in porous electrodes for NO_x⁻ reduction at high current densities.

The authors investigate the electronic structure of kagome CsCr₃Sb₅ using high-resolution angle-resolved photoemission spectroscopy and ab-initio calculations. The results identify CsCr₃Sb₅ as a strongly correlated Hund’s metal with incipient flat bands near the Fermi level.

Traditional cultured meat scaffolds employ animal-derived biomaterials or intricate manufacturing, but plant-based scaffolds offer an appealing alternative. Here the authors present a simple shortcut method to transform common vegetables into edible bioscaffolds via autoclaving, which mimics meat stiffness and microstructure.

Non-Hermiticity is usually considered detrimental to quasiparticle physics. Here, the authors show that such an assumption of Hermiticity can be lifted in the context of a lattice model containing two non-Hermitian Dirac cones, with one hosting amplifying Dirac quasiparticles and the other hosting decaying ones.

W. X. Zhao et al. study the higher-order topological insulator candidate Bi₄Br₄ by angle-resolved photoemission spectroscopy (ARPES) and ab-initio calculation. They provide strong evidence for the higher-order topological insulator phase, including a signature of the hinge states inside the (100) surface gap.

Heart failure is the most prevalent complication of acute myocardial infarction. Here, the authors show that circulating S100A8/A9 is a robust predictor and potentially causal medicator for heart failure post-acute myocardial infarction, as such could serve as a promising drug target for cardioprotection.

Mechanically rigid and geometrically stable nano-scaffolds decrease intermembrane spacing at the immunological synapse, leading to the exclusion of tyrosine phosphatase CD45 protein and enhancement of T-cell signalling.

Barley plants coat their organs with waxy diketones to protect against late-summer droughts. These diketones are formed by two enzymes, one diverting common fatty acids from normal metabolism and the other one linking two fatty acid units together.

The applications of human extended pluripotent stem cells (which can form both embryonic and extraembryonic lineages) demand a xeno-free culture condition; here, the authors provide a chemically defined and xeno-free culture system to do so.

By tracing promoter expression in lineage-mapped single cells, Xu et al. present a whole-body cartography of microRNA transcriptional activities during C. elegans embryogenesis and demonstrate its broad utility in multifaceted functional analyses.

Shao, Li, Liu et al. identify the GAS6–ATF3 axis as a central regulator of survival and proliferation of protective resident MerTK⁺ cardiac macrophages and show that GAS6 administration improves cardiac repair after ischemic–reperfusion injury in mice in an ATF3-dependent manner.

Human somatic cells were reprogrammed to human chemically induced pluripotent stem cells that demonstrate key features of embryonic stem cells.

2D multiferroic materials have garnered broad interests due to their magnetoelectric properties and multifunctional applications. Here, the authors discover a multiferroic feature in interfacial modulation synthesized wafer-scale one-unit-cell Cr₂S₃.

Despite many therapeutic improvements, mortality risk in patients with type A acute aortic dissection remains high. Here the authors construct a biomarker-guided risk stratification tool to predict death, which could potentially contribute to treatment decision-making and improvement of the prognosis.

Severe malaria is a life-threatening infection with limited treatment options. Here, using a medicinal chemistry approach starting from amicarbalide, Pegoraroet al. identify a compound that, when delivered intravenously, can cure Plasmodium falciparuminfection in a humanized mouse model.

Polymer materials that could spontaneously heal like tissues in living systems would significantly improve the safety, lifetime, energy efficiency and environmental impact of man-made materials. Now, a general multiphase design of autonomous self-healing elastomeric materials that do not require the input of external energy or healing agents is reported.

Optogenetic manipulation of protein localisation in cells involves the creation of fusions that can influence activity. Here the authors develop a near-infrared light-responsive aptamer-based system to regulate the nuclear-cytoplasmic shuttling of NF-κB subunit RelA.

Thoracic aortic dissection has a high fatality rate and no effective treatment. Here, the authors develop cationic nanoparticles for the delivery of miR-145 and show that they stabilize vascular structures and prevent further deterioration of the aorta in mouse models of the disease.

The mechanism of the charge density wave transition in quasi one-dimensional blue bronzes is still debated. Here, the authors report evidence of a Luttinger liquid in the normal state of blue bronzes and Holstein polarons below the transition temperature, revealing the important role of electron-phonon coupling in the transition.

Regeneration of skeletal muscle is accompanied by a transitory inflammatory phase. Here the authors show that the complement C3 component is activated following muscle injury, and signals through the alternative complement pathway to regulate immune cell infiltration and muscle regeneration.

NLRC5 facilitates cardiac repair by orchestrating autophagy through CAVIN1 degradation and CAV1/ATG12-5 modulation, positioning NLRC5 as a therapeutic target to mitigate post-MI damage and enhance recovery.

The Luttinger liquid is a theoretical concept used to describe interacting fermions in a 1D system. Now it is shown that the model also describes electron physics in η-Mo₄O₁₁, a quasi-2D material in which 1D chains cross each other.

Glucose is a promising feedstock for hydrogen production but the existing microbial reactors are expensive and suffer from low efficiencies. Here, the authors show an improved self-powered liquid catalyst fuel cell with a polymer-exchange membrane and polyoxometalate to catalyse glucose to hydrogen.