Qin, Dong, Tang, Chu et al. profile exosomal miRNAs from patients with stroke who have atherosclerosis, identifying selective upregulation of Novel-3 in the plasma. Using a mouse model of cerebral ischemia, they demonstrate the foam cell origin of Novel-3 and explore its neuroinflammatory role.
- Chuan Qin
- Ming-Hao Dong
- Dai-Shi Tian