Nature Search

Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment

Pathological neural communication drives the spread of the epileptic network and contributes to memory impairment in focal epilepsy. The authors show that closed-loop electrical stimulation in rodents can prevent this interaction and preserve long-term memory.

Jose J. Ferrero
Ahnaf R. Hassan
Jennifer N. Gelinas
ResearchOpen Access23 Jun 2025
Nature Neuroscience

P: 1-10
Publisher Correction: Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial

Jing Pan
Yue Tan
Xiaoming Feng
Amendments and Corrections16 Oct 2024
Nature Medicine

Volume: 31, P: 352
The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management

Zhongyao Hu
Changming Wang
Wendan Cheng
ResearchOpen Access15 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Building a eukaryotic chromosome arm by de novo design and synthesis

In Saccharomyces cerevisiae, the left arm of chromosome XII only requires 12 genes to maintain cell viability, whereas 25 genes are needed for robust fitness. Here the authors demonstrate that the entire arm can be replaced by a neochromosome with completely artificial sequences.

Shuangying Jiang
Zhouqing Luo
Junbiao Dai
ResearchOpen Access30 Nov 2023
Nature Communications

Volume: 14, P: 1-17
Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial

In a phase 1 trial, pediatric or adult patients with T-ALL who received CD5-targeted CAR-T cell therapy using cells from previous or newly matched donors showed an encouraging clinical response rate, with some severe adverse events that required attention and effective management.

Jing Pan
Yue Tan
Xiaoming Feng
Research01 Oct 2024
Nature Medicine

Volume: 31, P: 126-136
Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages

Adipose tissue macrophages are central to controlling inflammation in the context of obesity. Here the authors present a new infrared dye (IR-61) that accumulates in the mitochondria of these cells resulting in anti-inflammatory effects that counter obesity-associated pathology in mice.

Yawei Wang
Binlin Tang
Chunmeng Shi
ResearchOpen Access04 Jan 2021
Nature Communications

Volume: 12, P: 1-16
Performance assessment of BeiDou-3 PPP-B2b real time pre-cise point positioning

Yu Lin
Laiyong Song
Zelin Mu
ResearchOpen Access19 May 2025
Scientific Reports

Volume: 15, P: 1-15
The prognostic and therapeutic value of the tumor microenvironment and immune checkpoints in pancreatic neuroendocrine neoplasms

Zhijiang Chen
Shizhao Lin
Yu Pan
ResearchOpen Access21 Oct 2024
Scientific Reports

Volume: 14, P: 1-10
Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

Radiation damage causes DNA foci to form and senescence, causing ulcers. Here, the authors show that a naturally occurring adenosine analogue, cordycepin, prevents cell senescence via an increase in AMPK/NRF2, so blocking ulcers caused by radiation on skin/intestine/tongue damage in rodents.

Ziwen Wang
Zelin Chen
Chunmeng Shi
ResearchOpen Access10 Jun 2019
Nature Communications

Volume: 10, P: 1-16
The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division

The scaffold protein Miranda is required for the asymmetric segregation of the RNA binding protein Staufen to ganglion mother cells during Drosophila neuroblast division. Jia et al. map the interaction between these proteins and present a crystal structure of the interacting domains.

Min Jia
Zelin Shan
Wenning Wang
ResearchOpen Access01 Oct 2015
Nature Communications

Volume: 6, P: 1-12
C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial

Chimeric Antigen Receptor (CAR)-T cells show suboptimal efficacy in Acute Myeloid Leukaemia (AML). Here, the authors show that overexpression of C-JUN improves CAR-T cells efficacy in preclinical models for AML and report preliminary results of a pilot phase I clinical trial.

Shiyu Zuo
Chuo Li
Xiaoming Feng
ResearchOpen Access22 Jul 2024
Nature Communications

Volume: 15, P: 1-20
Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice

Sympathetic innervation of brown and white adipose tissue is shown to be promoted by zinc released from thermogenic adipocytes, revealing a positive feedback mechanism for regulation of thermogenesis and thereby energy expenditure.

Junkun Jiang
Donglei Zhou
Bing Luan
Research06 Mar 2023
Nature Metabolism

Volume: 5, P: 481-494
Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division

Polarized localization of Numb and Pon in Drosophila neuroblasts (NBs) enables their unequal segregation during asymmetric cell divisions. Here, the authors demonstrate liquid-liquid phase separation of Pon and Numb in NBs mediated by multivalent intermolecular interactions is required for their basal condensation.

Zelin Shan
Yuting Tu
Wenyu Wen
ResearchOpen Access21 Feb 2018
Nature Communications

Volume: 9, P: 1-16
The efficacy and cerebral mechanism of intradermal acupuncture for major depressive disorder: a multicenter randomized controlled trial

Xiaoting Wu
Mingqi Tu
Xiaomei Shao
ResearchOpen Access08 Dec 2024
Neuropsychopharmacology

Volume: 50, P: 1075-1083
Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes

The lancelet, or amphioxus, is an extant basal chordate that diverged from other chordate lineages about 550 million years ago. Here the authors sequence and assemble the diploid genome of a male adult of the Chinese lancelet, B. belcheri, and highlight genomic features that may have played an important role in the origin and evolution of vertebrates.

Shengfeng Huang
Zelin Chen
Anlong Xu
ResearchOpen Access19 Dec 2014
Nature Communications

Volume: 5, P: 1-12
Annexin A1 regulates inflammatory-immune response and reduces pancreatic and extra- pancreatic injury during severe acute pancreatitis

Shizhao Lin
Feihong Liang
Yu Pan
Research01 Mar 2025
Genes & Immunity

Volume: 26, P: 124-136
Constructing and validating a predictive nomogram for osteoporosis risk among Chinese single-center male population using the systemic immune-inflammation index

Hang Zhuo
Zelin Zhou
Xiaobing Jiang
ResearchOpen Access02 Jun 2024
Scientific Reports

Volume: 14, P: 1-10
Advancing robust all-weather desalination: a critical review of emerging photothermal evaporators and hybrid systems

All-weather solar-powered desalination systems are more demanding in terms of materials and system design compared to daytime-only systems. This Review discusses all-weather seawater evaporators, with a focus on photothermal conversion materials and their hybrid systems.

Yue Zhou
Zelin Wang
Chao Meng
ReviewsOpen Access14 Feb 2025
Communications Materials

Volume: 6, P: 1-20
High-dimensional single-cell analysis delineates radiofrequency ablation induced immune microenvironmental remodeling in pancreatic cancer

Qinglin Fei
Yu Pan
Heguang Huang
ResearchOpen Access27 Jul 2020
Cell Death & Disease

Volume: 11, P: 1-13
Frequent occurrence of CD19-negative relapse after CD19 CAR T and consolidation therapy in 14 TP53-mutated r/r B-ALL children

Jing Pan
Yue Tan
Xiaoming Feng
Research28 Apr 2020
Leukemia

Volume: 34, P: 3382-3387
Contribution of dermal-derived mesenchymal cells during liver repair in two different experimental models

Li Tan
Tingyu Dai
Chunmeng Shi
ResearchOpen Access29 Apr 2016
Scientific Reports

Volume: 6, P: 1-12
Global tissue transcriptomic analysis to improve genome annotation and unravel skin pigmentation in goldfish

Wu Gan
Yu-Wen Chung-Davidson
Jianfeng Ren
ResearchOpen Access19 Jan 2021
Scientific Reports

Volume: 11, P: 1-14
Noninvasive and portable stroke type discrimination and progress monitoring based on a multichannel microwave transmitting–receiving system

Jia Xu
Jingbo Chen
Mingsheng Chen
ResearchOpen Access10 Dec 2020
Scientific Reports

Volume: 10, P: 1-13
LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia

Chaoying Ni
Wei Jiang
Cunyou Zhao
Research03 Feb 2020
Molecular Psychiatry

Volume: 26, P: 4511-4528
Non-cultured dermal-derived mesenchymal cells attenuate sepsis induced by cecal ligation and puncture in mice

Yu Wang
Li Tan
Chunmeng Shi
ResearchOpen Access20 Nov 2015
Scientific Reports

Volume: 5, P: 1-16
A novel full-human CD22-CAR T cell therapy with potent activity against CD22^low B-ALL

Yue Tan
Haodong Cai
Jing Pan
CorrespondenceOpen Access10 Apr 2021
Blood Cancer Journal

Volume: 11, P: 1-6
Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury

Zelin Chen
Xin Wang
Chunmeng Shi
ResearchOpen Access02 Feb 2017
Cell Death & Disease

Volume: 8, P: e2573
Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

Yi Zhong
Xiao Chang
Xiao-Kui Guo
Research22 Mar 2011
Cell Research

Volume: 21, P: 1210-1229

Search

Closed-loop electrical stimulation prevents focal epilepsy progression and long-term memory impairment

Publisher Correction: Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial

The comparative efficacy of L-glutamine, celecoxib, and glucosamine sulfate in osteoarthritis management

Building a eukaryotic chromosome arm by de novo design and synthesis

Allogeneic CD5-specific CAR-T therapy for relapsed/refractory T-ALL: a phase 1 trial

Improvement of obesity-associated disorders by a small-molecule drug targeting mitochondria of adipose tissue macrophages

Performance assessment of BeiDou-3 PPP-B2b real time pre-cise point positioning

The prognostic and therapeutic value of the tumor microenvironment and immune checkpoints in pancreatic neuroendocrine neoplasms

Cordycepin prevents radiation ulcer by inhibiting cell senescence via NRF2 and AMPK in rodents

The structural basis of Miranda-mediated Staufen localization during Drosophila neuroblast asymmetric division

C-JUN overexpressing CAR-T cells in acute myeloid leukemia: preclinical characterization and phase I trial

Thermogenic adipocyte-derived zinc promotes sympathetic innervation in male mice

Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division

The efficacy and cerebral mechanism of intradermal acupuncture for major depressive disorder: a multicenter randomized controlled trial

Decelerated genome evolution in modern vertebrates revealed by analysis of multiple lancelet genomes

Annexin A1 regulates inflammatory-immune response and reduces pancreatic and extra- pancreatic injury during severe acute pancreatitis

Constructing and validating a predictive nomogram for osteoporosis risk among Chinese single-center male population using the systemic immune-inflammation index

Advancing robust all-weather desalination: a critical review of emerging photothermal evaporators and hybrid systems

High-dimensional single-cell analysis delineates radiofrequency ablation induced immune microenvironmental remodeling in pancreatic cancer

Frequent occurrence of CD19-negative relapse after CD19 CAR T and consolidation therapy in 14 TP53-mutated r/r B-ALL children

Contribution of dermal-derived mesenchymal cells during liver repair in two different experimental models

Global tissue transcriptomic analysis to improve genome annotation and unravel skin pigmentation in goldfish

Noninvasive and portable stroke type discrimination and progress monitoring based on a multichannel microwave transmitting–receiving system

LncRNA-AC006129.1 reactivates a SOCS3-mediated anti-inflammatory response through DNA methylation-mediated CIC downregulation in schizophrenia

Non-cultured dermal-derived mesenchymal cells attenuate sepsis induced by cecal ligation and puncture in mice

A novel full-human CD22-CAR T cell therapy with potent activity against CD22^low B-ALL

Increase in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury

Comparative proteogenomic analysis of the Leptospira interrogans virulence-attenuated strain IPAV against the pathogenic strain 56601

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