Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–20 of 20 results
Advanced filters: Author: Zemer Gitai Clear advanced filters

  • Exposing Caenorhabditis elegans to non-coding small RNAs from pathogenic Pseudomonas aeruginosa induces avoidance behaviours in treated worms and their progeny, which reveals how C. elegans discriminates between bacterial species in its microbial environment.

    • Rachel Kaletsky
    • Rebecca S. Moore
    • Coleen T. Murphy
    Research
    Nature
    Volume: 586, P: 445-451

  • Applying a classical solution to a cutting-edge problem, two groups used bacterial conjugation to construct Escherichia coli double mutants on a genome-wide scale. This will allow comprehensive genetic interaction screens in bacteria for the first time.

    • Thomas J Silhavy
    • Zemer Gitai
    News & Views
    Nature Methods
    Volume: 5, P: 759-760

  • M3-seq uses combinatorial indexing alongside post hoc rRNA depletion in a single-cell RNA sequencing approach that reveals bacterial heterogeneity and rare populations during antibiotic stress and phage infection, as well as bet-hedging responses during growth.

    • Bruce Wang
    • Aaron E. Lin
    • Zemer Gitai
    ResearchOpen Access
    Nature Microbiology
    Volume: 8, P: 1846-1862

  • Surface association and quorum sensing regulate bacterial community behaviours such as biofilm formation and motility. Here, Chuang et al. show that surface association promotes stronger quorum-sensing responses in Pseudomonas aeruginosa by upregulating the master regulator LasR.

    • Sara K. Chuang
    • Geoffrey D. Vrla
    • Zemer Gitai
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-10

  • Type IV pili (T4P) are retractile appendages used by bacteria for DNA uptake and other purposes. T4P extension is thought to occur through the action of a single motor protein, PilB. Here, Ellison et al. show that T4P synthesis in Acinetobacter baylyi depends not only on PilB but also on an additional, distinct motor, TfpB.

    • Courtney K. Ellison
    • Triana N. Dalia
    • Ankur B. Dalia
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-9

  • Bacteria can form organized multicellular communities through regulation of cell growth, motility, shape and differentiation. Here, Ellison et al. show that bacterial multicellular development can also be driven by specific patterns of localization of appendages known as type IV pili.

    • Courtney K. Ellison
    • Chenyi Fei
    • Zemer Gitai
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-9

  • The metabolic enzyme CTP synthase (CtpS) of Caulobacter crescentus can polymerize into cytoskeletal filaments. It functions together with the intermediate filament protein crescentin to control cell shape.

    • Michael Ingerson-Mahar
    • Ariane Briegel
    • Zemer Gitai
    Research
    Nature Cell Biology
    Volume: 12, P: 739-746

  • Optogenetically controlling the assembly of enzyme clusters enhances product formation and specificity during deoxyviolacein biosynthesis by decreasing concentrations of intermediate metabolites and reducing flux through competing pathways.

    • Evan M. Zhao
    • Nathan Suek
    • Jared E. Toettcher
    Research
    Nature Chemical Biology
    Volume: 15, P: 589-597

  • A combination of microfluidic devices, transcriptomic analyses and reporter strains shows that Pseudomonas aeruginosa modulates gene expression in response to shear flow. This process, termed rheosensing, does not require known surface sensors and is regulated by the alternative sigma factor FroR.

    • Joseph E. Sanfilippo
    • Alexander Lorestani
    • Zemer Gitai
    Research
    Nature Microbiology
    Volume: 4, P: 1274-1281

  • The human enzyme CTP synthase forms polymeric filaments with increased catalytic activity, in contrast to the inactive filaments formed by bacterial CTP synthase. Cryo-EM and crystallographic analyses explain the structural bases for those different behaviors.

    • Eric M Lynch
    • Derrick R Hicks
    • Justin M Kollman
    Research
    Nature Structural & Molecular Biology
    Volume: 24, P: 507-514

  • The potential advantages of specific cell shapes among microbes are unclear. Here, the authors show that the curved shape of the bacterium Caulobacter crescentus, which lives in lakes and streams, helps cells to colonize surfaces in the presence of fluid flow.

    • Alexandre Persat
    • Howard A. Stone
    • Zemer Gitai
    Research
    Nature Communications
    Volume: 5, P: 1-9

  • The actin-like protein MreB coordinates the synthesis of the cell wall, which determines cell shape in bacteria. Here, Bratton et al. show that the transmembrane protein RodZ modulates MreB polymer number and curvature preference, contributing to the cylindrical uniform shape of E. coli cells.

    • Benjamin P. Bratton
    • Joshua W. Shaevitz
    • Randy M. Morgenstein
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-11

  • Mammalian mitochondria use folate-bound one-carbon units generated by the enzyme SHMT2 to methylate tRNA, and this modification is required for mitochondrial translation and thus oxidative phosphorylation.

    • Raphael J. Morscher
    • Gregory S. Ducker
    • Joshua D. Rabinowitz
    Research
    Nature
    Volume: 554, P: 128-132

  • Mitochondrial ribosomes (mitoribosomes) translate a unique set of genes whose products are essential for cellular respiration. This protocol provides a modified ribosome profiling procedure suitable for studying translation within mitochondria.

    • Sophia Hsin-Jung Li
    • Michel Nofal
    • Zemer Gitai
    Protocols
    Nature Protocols
    Volume: 16, P: 2802-2825

  • An elegant mathematical model supported by experiments in Escherichia coli demonstrates how clustering enzymes can efficiently channel intermediates from one enzyme to the next, facilitating rational engineering of metabolism.

    • Michele Castellana
    • Maxwell Z Wilson
    • Ned S Wingreen
    Research
    Nature Biotechnology
    Volume: 32, P: 1011-1018