This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
269,00 € per year
only 22,42 € per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Data availability
The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
References
Reddy RL. Mobilization and collection of peripheral blood progenitor cells for transplantation. Transfus Apher Sci. 2005;32:63–72.
Rowley SD, Donaldson G, Lilleby K, Bensinger WI, Appelbaum FR. Experiences of donors enrolled in a randomized study of allogeneic bone marrow or peripheral blood stem cell transplantation. Blood. 2001;97:2541–8.
Arai S, Klingemann HG. Hematopoietic stem cell transplantation: bone marrow vs. mobilized peripheral blood. Arch Med Res. 2003;34:545–53.
Rosenbaum ER, O’connell B, Cottler-Fox M. Validation of a formula for predicting daily CD34+ cell collection by leukapheresis. Cytotherapy. 2012;14:461–6.
Kayser S, Schlenk RF, Steiner M, Klüter H, Wuchter P. Predicting successful hematopoietic stem cell collection in healthy allogeneic donors. Transfus Med Hemother. 2023;50:396–402.
Almeida-Neto CD, Rocha V, Moreira FR, Hamasaki DT, Farias MCD, Arrifano AM, et al. Validation of a formula predictive of peripheral blood stem cell yield and successful collection in healthy allogeneic donors. Hematol Transfus Cell Ther. 2020;42:164–5.e5.
Chen J, Burns K, Kennedy M, Segura FJ, Garcia S, Leveque C. A method to predict the yield of peripheral blood stem cells collected by large volume leukapheresis. J Blood Lymph. 2017;7:1000160.
Piccirillo N, Putzulu R, Metafuni E, Massini G, Fatone F, Corbingi A, et al. Peripheral blood allogeneic stem cell mobilization: can we predict a suboptimal mobilization? Transfus Med Rev. 2023;37:150725.
DiPersio JF, Micallef IN, Stiff PJ, Bolwell BJ, Maziarz RT, Jacobsen E, et al. Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin’s Lymphoma. J Clin Oncol. 2009;27:4767–73.
Cid J, Monsalvo S, Castillo C, Pascual C, Moreno-Jiménez G, López-Parra M, et al. Addition of plerixafor to G-CSF in poor mobilizing healthy related donors overcame mobilization failure: an observational case series on behalf of the Grupo Español de Trasplante Hematopoyético (GETH). Transfus Apher Sci. 2021;60:103052.
Hölig K, Schmidt H, Hütter G, Kramer M, Teipel R, Heidrich K, et al. Salvage treatment with plerixafor in poor mobilizing allogeneic stem cell donors: results of a prospective phase II-trial. Bone Marrow Transpl. 2021;56:635–45.
Meldgaard Knudsen L, Nikolaisen K, Gaarsdal E, Johnsen HE. Kinetic studies during peripheral blood stem cell collection show CD34+ cell recruitment intra‐apheresis. J Clin Apheresis. 2001;16:114–9.
Author information
Authors and Affiliations
Contributions
JYT, LPK and YCL was responsible for extracting and analysing data, interpreting results, updating references lists and creating tables and figures. JYT was responsible for statistical analysis and writing of the manuscript. YCL and LPK were responsible for editing and revisions of the manuscript. LPK, YKW, KKH, AHYT, TGS, JKSQ, LCKN, HT, FWIL, CHA, TT, GG, RBS, GX, JL, JJL, ZJS, LLW, MP, LKT, YTG, WYKH, AYLH and YCL provided donor data and all co-authors provided feedback on the manuscript.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Ethics approval and consent to participate
Data were derived from our transplant database and electronic record with Institutional review board (IRB) approval (ECOS 2015-2419), and all donors have given prior consent to usage of their clinical and laboratory results.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Supplementary information
Rights and permissions
About this article
Cite this article
Tan, JY., Koh, LP., Woon, YK. et al. A formula using day 4 parameters to predict next-day peripheral blood stem cell yield in healthy haematopoietic stem cell donors. Bone Marrow Transplant 60, 549–551 (2025). https://doi.org/10.1038/s41409-024-02503-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41409-024-02503-z
