Fig. 3: Structural details of the SENP5CD complex with SUMO1 and SUMO2.
From: Structural basis for the human SENP5’s SUMO isoform discrimination
a Close-up view of the C-terminal tail of human SUMO2 (yellow) in complex with SENP5CD (blue). Binding side-chain residues in the contact area of substrate and enzyme are shown in stick representation and labelled. Hydrogen bonds are represented by dashed red lines. b Similar close-up views of the C-terminal of SUMO2 (gray) in complex with SENP2 (upper) and SENP7 (below). c (Upper) Close-up view of the ribbon representation of SENP5CD-SUMO2 interface in two orthogonal views. Binding side-chain residues in the contact area are labelled and shown in stick representation. Hydrogen bonds and charged interactions are represented by dashed red lines. (Below) Similar close-up view of the ribbon representation of SENP5CD-SUMO1 interface in two orthogonal views.
