Fig. 4: Extended applications of radical trifluoromethylamidations.
From: Direct synthesis of N-trifluoromethyl amides via photocatalytic trifluoromethylamidation
A Radical trifluoromethylamidations of compounds 5. B Radical trifluoromethylamidations of compounds 7. C Radical trifluoromethylamidation of compound 9. D Radical trifluoromethylamidation of compound 11. E Radical trifluoromethylamidation of compound 13. F Radical trifluoromethylamidation of compound 15. General reaction conditions: Ir(dFppy)3 (0.003 mmol), DCM (9 mL), Blue LEDs, under N2, RT, 12 h, isolated yields. a1e (0.3 mmol), 5 (0.9 mmol). b1e (0.3 mmol), 7 (0.9 mmol). c1i (0.3 mmol), 9 (0.9 mmol). d1e (0.45 mmol), 11 (0.3 mmol). e1e (0.45 mmol), 13 (0.3 mmol). f1e (0.3 mmol), 15 (0.9 mmol).
