Fig. 5: Correlation between FERscore and Cancer-associated fibroblasts (CAFs).
From: Efficacy of FERscore in predicting sensitivity to ferroptosis inducers in breast cancer
A Differences in signatures of TGFβ-related pathways between high- and low-FERscore groups. Pan-F-TBRS: pan-fibroblast TGFβ response signature. Box plots indicate median; 25th and 75th percentiles; ***P < 0.001; two-tailed t-tests. B Correlation between expression of the 55 ferroptosis-related genes as well as FERscores and the infiltrated CAF levels. C Candidate CAF-associated cytokines. D Differences in the expression of 75 cytokines between high- and low-FERscore groups from 3 clinical cohorts, including METABRIC, TCGA-BRCA and GSE20685 datasets.
