Extended Data Fig. 5: MW-TMPs activate DCs and enhance the antigen presentation ability of DCs, related to Fig. 4. | Nature Nanotechnology

Extended Data Fig. 5: MW-TMPs activate DCs and enhance the antigen presentation ability of DCs, related to Fig. 4.

From: Tumour-derived microparticles obtained through microwave irradiation induce immunogenic cell death in lung adenocarcinoma

Extended Data Fig. 5

(a) Heatmap description of marker genes expression of cDC1s, mregDCs and cDC2s. (b) Heatmap of the differential genes in DCs among clusters. (c) The antigen-presenting gene expression on mregDCs. Box plots display median (center line), IQR (box), 1.5×IQR whiskers, and outliers (open circles). Min/max represent the range of non-outlier values (n = 3). (d) DCs infiltration in tumors (n = 5). (e) Distribution of CD103 + cDC1s in tumor tissues (n = 5). (f) Distribution of CCR7+mregDCs in tumor tissues (n = 5). (g) The proportion of CD86+ in CCR7+mregDCs (n = 5). The data in (d-g) are shown in analytic plots as mean ± s.d. Ordinary one-way ANOVA was used among three groups in (d-g). The exact p value was noted.

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