Extended Data Fig. 7: Extended KCC2 related data from immature GABA neurons.
From: Phenotypic complexities of rare heterozygous neurexin-1 deletions
(a) Transcriptomic comparison of SLC12A5 expression across DIV14 and DIV35 RNASeq timepoints, compared via a two-tailed mixed effects model-time (F1,28 = 499.1 p <2.2E-16), sample information correspond Fig. 1. (b,c) MEA tests from pre- and post- treatment of 10uM GABAzine (n/d = 28/2 | 1 representative batch) compared via two-tailed paired student’s t-test for time-linked comparison (t = 9.739, df = 27; p = 2.497E-10) and two-tailed unpaired student’s t-test for pre/post activity foldchange, (t = 2.380, df = 54; p = 0.0209). Data represented as mean ± sem. n reported as samples/donors | independent batches.
