Extended Data Fig. 9: Significant reduction in Basal-B like cells following diphtheria toxin treatment during inflammation. | Nature Genetics

Extended Data Fig. 9: Significant reduction in Basal-B like cells following diphtheria toxin treatment during inflammation.

From: JAK/STAT signaling maintains an intermediate cell population during prostate basal cell fate determination

Extended Data Fig. 9

a,b, Immunofluorescence staining of Trp63, Ck8, ZsGreen and tdTomato in vehicle-treated (a) and diphtheria toxin-treated (b) Bas-B-DTR mouse prostates. c,d, Flow plots showing the percentage of Basal-B cells (ZsGreen+tdTomato+) among basal cells (ZsGreen+) of vehicle-treated (c) and diphtheria toxin- treated (d) Basal-B-DTR mouse anterior prostates. e. A bar graph showing Basal-B cell in ZsGreen+ basal cells of vehicle-treated (n = 5 mice) and diphtheria toxin-treated (n = 3 mice) Bas-B-DTR prostates. Data are shown as the mean ± SD. Data were analyzed by unpaired two-tailed Student’s t test; **p < 0.01, ***p < 0.001. Scale bars, 50μm.

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