Extended Data Fig. 8: Comparison between embeddings generated by CellLENS and SpaGCN on CosMx HCC data.

While initially designed for spot-level spatial-omics data, SpaGCN could run on the whole CosMx-SMI human HCC data ( ~ 50k cells). We compared the cell type delineation ability between the embeddings from CellLENS and SpaGCN. The figure setup is the same as described in Fig. 5. SpaGCN failed to identify the various Macrophage subpopulations captured by CellLENS.