Extended Data Fig. 2: Impedance of sensing and stimulation electrode contacts reflect long term stability at device-tissue interface.

(a) Impedance in kOhms of sensing and stimulation electrode contacts in the left (left panel) and right (right panel) VC/VS of P3. Blue points indicate impedance between the two sensing contacts. Green points indicate the impedance between the deepest (light green) and shallowest (dark green) sensing contact and the INS case. Light red points indicate the impedance between the stimulation contact and the INS case. Sense and stimulation electrode contacts on the Medtronic 3387 leads are visualized to the right of each panel, with contact 0 as the deepest contact on the left, and contact 8 as the deepest contact on the right. Light green indicates the deepest sensing contact, Green indicates the shallowest sensing contact, and light red indicates the stimulation contact. Black contacts are unused. (b) Impedance in kOhms of sensing and stimulation electrode contacts in the left (left panel) and right (right panel) VC/VS of P4. Gray shaded region indicates the timespan when sensing and stimulation contacts correspond to the Medtronic 3387 lead diagram labelled with “A”, whereas the following timespan with no shading corresponds to the Medtronic 3387 lead diagram labelled with “B”. Elsewise, the format is identical to panel a. (c) Impedance in kOhms of sensing and stimulation electrode contacts in the left (left panel) and right (right panel) VC/VS of P5. Format is identical to panel A.