Extended Data Fig. 3: Depletion of ACS-related bacteria SGB 4712 replicates in an independent validation cohort. | Nature Medicine

Extended Data Fig. 3: Depletion of ACS-related bacteria SGB 4712 replicates in an independent validation cohort.

From: Metabolomic and microbiome profiling reveals personalized risk factors for coronary artery disease

Extended Data Fig. 3

(a) Box plots showing the relative abundance of the unknown bacterial species SGB 4712 (y-axis: center, median; box, IQR; whiskers, 1.5×IQR; log scaled) in our ACS and matched controls (x-axis; n = 80 each). The P-value shown is computed using the two-sided Mann–Whitney U-test. (b) Relative abundance of the unknown bacterial species SGB 4712 (y-axis: center, median; box, IQR; whiskers, 1.5×IQR; log scaled) in four groups from the MetaCardis validation cohort (x-axis; HC, healthy controls, n = 275; MMC, metabolically matched controls, n = 218; UMCC, untreated metabolically compromised controls, n = 211; IHD, ischaemic heart disease, n = 319). The P-value shown is computed using the two-sided Mann–Whitney U-test. r.a., relative abundance.

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