Extended Data Fig. 3: Schematic diagram of timing of blood sample collection and administration of therapeutic modalities compared to day of admission (day 0) in MIS-C patients.

Red circles identify first blood samples collected prior to administration of glucocorticoids, IVIG or biologics. For PIMS-006, PIMS-016, PIMS-023, PIMS-032, PIMS-036, PIMS-055, TO-006, TO-034, NAP013, the first blood sample was obtained the same day (and immediately prior to) therapeutic interventions with glucocorticoids, IVIG and/or biologics were started. *Levels of soluble biomarkers were not measured in the first blood samples obtained from NAP012 and TO-053.