Extended Data Fig. 5: Associations between maternal polygenic risk score for IBD, UC, Crohn’s, and autism factor mean score in the children, at 13 P-value thresholds for PRS generation. | Nature Medicine

Extended Data Fig. 5: Associations between maternal polygenic risk score for IBD, UC, Crohn’s, and autism factor mean score in the children, at 13 P-value thresholds for PRS generation.

From: Parental inflammatory bowel disease and autism in children

Extended Data Fig. 5

n = 7,348 mother–child pairs. Data are presented as beta coefficients and 95% CIs. Calculated by linear regression of the mothers’ PRS for IBD, UC, or Crohn’s on the standardized autism factor mean score in the children, adjusted for child’s sex and the first ten principal components of the ALSPAC genotype data.

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