Fig. 5: Replication and generalization of the findings using electronic health records data.

Kaplan–Meier curves represent the cumulative incidence of cognitive deficits between those with high versus low fibrinogen (or D-dimer) and CRP level ≤10 mg l−1. The same analysis conducted in people without COVID-19 (bottom). Curves represent the Kaplan–Meier estimates and shading around curves represents 95% CI. P values are derived from log-rank tests, are two-sided and not adjusted for multiple comparisons. The same figures within the COVID-19 cohort wherein the criterion on CRP is relaxed to include all those with a CRP ≤ 20 mg l−1 or is removed altogether are presented as Extended Data Fig. 5.