Extended Data Fig. 10: Tissue gene expression of COL4A1 and COL4A2.
Gene expression of (a) COL4A1 and (b) COL4A2 was queried in GTEx v8 portal (dbGaP Accession phs000424.v8. p2) for all available human tissues. Expression values shown in transcripts per million (TPM) were calculated from a gene model with isoforms collapses to a single gene, for which box plots are shown as median, 25%, and 75%. Outliers are defined as points outside the 1.5x interquartile range. NAdipose - Subcutaneous = 663, NAdipose - Visceral = 541, NAdrenal Gland = 258, NArtery - Aorta = 432, NArtery - Coronary = 240, NArtery - Tibial = 663, NBladder = 21, NBrain - Amygdala = 152, NBrain - Anterior cingulate cortex = 176, NBrain - Caudate = 246, NBrain - Cerebellar Hemisphere = 215, NBrain - Cerebellum = 241, NBrain - Cortex = 255, NBrain - Frontal Cortex = 209, NBrain - Hippocampus = 197, NBrain- Hypothalamus - =202, NBrain - Nucleus accumbens (basal ganglia)=246, NBrain - Putamen (basal ganglia)=205, NBrain - Spinal cord (cervical c-1) = 159, NBrain - Substantia nigra = 139, NBreast - Mammary Tissue = 459, NCells - Cultured fibroblasts = 504, NCells - EBV-transformed lymphocytes = 174, NCervix - Ectocervix = 9, NCervix - Endocervix = 10, NColon - Sigmoid = 373, NColon - Transverse = 406, NEsophagus - Gastroesophageal Junction = 375, NEsophagus - Mucosa = 555, NEsophagus - Muscularis=515, NFallopian Tube = 9, NHeart - Atrial Appendage = 429, NHeart - Left Ventricle = 432, NKidney - Cortex = 85, NKidney - Medulla = 4, NLiver = 226, NLung = 578, NMinor Salivary Gland = 162, NMuscle - Skeletal = 803, NNerve - Tibial = 619, NOvary = 180, NPancreas = 328, NPituitary = 283, NProstate = 245, NSkin - Not Sun Exposed (Suprapubic)=604, NSkin - Sun Exposed (Lower leg)=701, NSmall Intestine - Terminal Ileum = 187, NSpleen = 241, NStomach = 359, NTestis = 361, NThyroid = 653, NUterus = 142, NVagina = 156, NWhole Blood = 755.
