Extended Data Fig. 1: Schematic of the literature review workflow for transplant omics datasets. | Nature Medicine

Extended Data Fig. 1: Schematic of the literature review workflow for transplant omics datasets.

From: Decoding the hallmarks of allograft dysfunction with a comprehensive pan-organ transcriptomic atlas

Extended Data Fig. 1

A systematic search of the GEO and ArrayExpress databases using terms related to heart, lung, liver, and kidney transplants, yielded 13,419 datasets. Datasets underwent scrutiny for inclusion, excluding non-human or those lacking proper controls, defined as stable functioning grafts. Data were then extracted and normalized using various methods appropriate to the data type. The PROMAD repository was created, comprising 168 processed datasets available for research access, with 150 transcriptomic datasets selected for our study. Non-coding region datasets, while excluded from this study, were also included in PROMAD.

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