Correction to: Nature Medicine https://doi.org/10.1038/s41591-024-03060-0, published online 1 June 2024

In the version of the article initially published, in Extended Data Fig. 1, under “Part 1B”, “5 mg QD” originally read “3 dose levels” and “n=9” was missing from that box. There was originally an additional “Cohort 1 (5 mg QD, n=9)” box that has now been removed. Under “Part “2A”, the text “fulvestrant 500 mg” originally preceded “(n=35)”. In Extended Data Fig. 5, “(confirmed)” has been removed from both graph legends, which originally read “Best overall response (confirmed)”. In Extended Data Table 1, the title of Table 1B has been corrected from “PF-07248144 dose and DLT relationship” to “Bayesian Logistic Regression Model: Predicted probability of DLT”. These corrections have been made to the HTML and PDF versions of the article.