Table 1 Characteristics of study participants for each of the three cohorts
 | UKB (n = 45,441) | CKB (n = 3,977) | FinnGen (n = 1,990) |
---|---|---|---|
Age | |||
Mean (s.d.) | 57 (8.2) | 57 (12) | 56 (15) |
Range (years) | 39–71 | 30–78 | 19–78 |
Sex | |||
Female | 24,579 (54.1%) | 2,137 (53.7%) | 1,032 (51.9%) |
BMI (kg m−2) | |||
Mean (s.d.) | 27 (4.8) | 24 (3.6) | 26 (4.5) |
Ethnicity | |||
White | 42,320 (93.1%) | – | – |
Asian | 1,016 (2.2%) | – | – |
Black | 1,114 (2.5%) | – | – |
Mixed | 293 (0.6%) | – | – |
Other | 554 (1.2%) | – | – |
Geographic region | |||
Gansu (rural) | – | 397 (10.0%) | – |
Haikou (urban) | – | 298 (7.5%) | – |
Harbin (urban) | – | 598 (15.0%) | – |
Henan (rural) | – | 493 (12.4%) | – |
Hunan (rural) | – | 462 (11.6%) | – |
Liuzhou (urban) | – | 379 (9.5%) | – |
Qingdao (urban) | – | 415 (10.4%) | – |
Sichuan (rural) | – | 341 (8.6%) | – |
Suzhou (urban) | – | 252 (6.3%) | – |
Zhejiang (rural) | – | 342 (8.6%) | – |
Incident diabetes | |||
Yes | 2,781 (6.1%) | 160 (4.0%) | – |
Incident IHD | |||
Yes | 4,546 (10.0%) | 2,121 (53.3%) | – |
Incident all stroke | |||
Yes | 1,362 (3.0%) | 566 (14.2%) | – |
Incident ischemic stroke | |||
Yes | 1,182 (2.6%) | 521 (13.1%) | – |
Incident COPD | |||
Yes | 2,059 (4.5%) | 178 (4.5%) | – |
Incident chronic liver diseases | |||
Yes | 1,011 (2.2%) | 39 (1.0%) | – |
Incident CKDs | |||
Yes | 2,626 (5.8%) | 52 (1.3%) | – |
All-cause mortality | |||
Dead | 4,828 (10.6%) | 1,426 (35.9%) | 22 (1.1%) |