Extended Data Fig. 6: Differential abundance comparison of specific pathogens of interest between time points in the in DNA-seq samples of the doxy-PEP arm (n = 80). | Nature Medicine

Extended Data Fig. 6: Differential abundance comparison of specific pathogens of interest between time points in the in DNA-seq samples of the doxy-PEP arm (n = 80).

From: Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Extended Data Fig. 6

Bacterial abundance of several pathogens of interest (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, and Clostroidioides difficile) were compared between day-0 and month-6 samples in the doxy-PEP arm. P-values were calculated using the Wilcoxon rank-sum test and adjusted for multiple comparisons. Boxplot elements include a center line (median), box limits (upper and lower quartiles), whiskers (1.5x interquartile range). Abbreviation: NT RPM, nucleotide reads per million.

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