Fig. 3: Impact of doxy-PEP use on tetracycline and non-tetracycline ARGs for DNA-seq samples and RNA-seq samples. | Nature Medicine

Fig. 3: Impact of doxy-PEP use on tetracycline and non-tetracycline ARGs for DNA-seq samples and RNA-seq samples.

From: Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Fig. 3

Tetracycline ARG richness (a,b) and tetracycline ARG proportion of resistome mass (c,d) were compared between SOC and DP arms at each visit and over time (DNA-seq: n = 127; RNA-seq: n = 86). e,f, The proportion of the resistome mass by ARG classes over time within the DP arm (DNA-seq: n = 80; RNA-seq: n = 55). P values were calculated using the two-sided Wilcoxon rank-sum test and adjusted for multiple comparisons. Box plot elements include a center line (median), box limits (upper and lower quartiles) and whiskers (1.5× IQR).

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