Fig. 4: Impact of doxy-PEP use on tetracycline ARGs by number of doxycycline doses received for DNA-seq samples and RNA-seq samples. | Nature Medicine

Fig. 4: Impact of doxy-PEP use on tetracycline ARGs by number of doxycycline doses received for DNA-seq samples and RNA-seq samples.

From: Impact of doxycycline post-exposure prophylaxis for sexually transmitted infections on the gut microbiome and antimicrobial resistome

Fig. 4

A test of trend was used to compare tetracycline ARG richness (a,c) and proportion of tetracycline ARG mass to resistome mass by number of doxycycline doses received (b,d) (DNA-seq: n = 127; RNA-seq: n = 86). P values were calculated using the two-sided Wilcoxon rank-sum test and adjusted for multiple comparisons. The two-sided Spearman’s rank correlation test was used to calculate Spearman’s ρ and P value. Box plot elements include a center line (median), box limits (upper and lower quartiles) and whiskers (1.5× IQR).

Back to article page