Extended Data Fig. 5: No correlation between vaccine-specific IgG BM ASC responses and the time windows of the vaccine. | Nature Medicine

Extended Data Fig. 5: No correlation between vaccine-specific IgG BM ASC responses and the time windows of the vaccine.

From: SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination

Extended Data Fig. 5

BM (a) Flu, (b) Tet, and (c) S2P IgG LLPC, Non-LLPC, and total ASC responses in all examined subjects following the vaccine exposure time (time since the most recent (a) Flu, (b) Tet, or (c) the first SARS-CoV-2 vaccine). Data were generated from 17, 15, and 19 different SARS-CoV-2 vaccinated subjects for BM LLPC, Non-LLPC, and total ASC, respectively. Correlations were assessed using simple linear regression analysis performed with GraphPad Prism (GraphPad Software). The exact p values for vaccine-specific LLPC, Non-LLPC, and total ASC are 0.9397, 0.8563, and 0.7455, respectively (a); 0.1806, 0.2898, and 0.0952, respectively (b); and 0.3202, 0.3635, and 0.2862, respectively (c). Subjects yielding sufficient ASC for LLPC and Non-LLPC subsets included.

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