Extended Data Fig. 8: No correlation between S2P IgG BM ASC responses and the time windows of the SARS-CoV-2 vaccine in both vaccinees and infected vaccinees (Vaccine+Infection). | Nature Medicine

Extended Data Fig. 8: No correlation between S2P IgG BM ASC responses and the time windows of the SARS-CoV-2 vaccine in both vaccinees and infected vaccinees (Vaccine+Infection).

From: SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination

Extended Data Fig. 8

BM S2P IgG SC responses in vaccinated versus hybrid subjects stratified by time since (a) the first or (b) the most recent (prior to BM aspiration) SARS-CoV-2 vaccine. The exposure time for infection in the hybrid subjects not shown. For BM LLPC, data were generated from 12 and 5 different subjects of Vaccine and of Vaccine+Infection, respectively. For BM Non-LLPC, data were generated from 12 and 3 different subjects of Vaccine and of Vaccine+Infection, respectively. The exact p values for Vaccine/LLPC, Vaccine+Infection/LLPC, Vaccine/Non-LLPC, and Vaccine+Infection/Non-LLPC are 0.3192, 0.6529, 0.3446, and 0.9254, respectively (a); and 0.4933, 0.7301, 0.8004, and 0.7128, respectively (b). Subjects yielding sufficient ASC for LLPC and Non-LLPC subsets included.

Source data

Back to article page