Extended Data Fig. 10: Assessment of spinal cord stimulation induced responses.
From: First-in-human study of epidural spinal cord stimulation in individuals with spinal muscular atrophy
a, Quantification of percent change in area under the curve of peak-to-peak TMS responses post-explant vs six week follow up across all intensities tested. Abbreviations: ST, Semitendinosus; BF, Bicep Femoris; VL, Vastus Lateralis; RP, Rectus Femoris Proximal; RD, Rectus Femoris Distal; G, Gastrocnemius; TA, Tibialis Anterior. Error bars are the mean and 95% CI of the mean peak-to-peak responses (bootstrap N = 10,000). b, The SCS parameters used and the resulting plots representing the normalized peak-to-peak response as a function of SCS amplitude. Shaded areas correspond to standard error across responses, while thick lines are the means across responses.
