Rusty Gage describes how evidence for neurogenesis in the adult human hippocampus shaped our understanding of learning, memory and mental health.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
27,99 € / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
209,00 € per year
only 17,42 € per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Eriksson, P. S. et al. Nat. Med. 4, 1313–1317 (1998).
Ray, J., Peterson, D. A., Schinstine, M. & Gage, F. H. Proc. Natl Acad. Sci. USA 90, 3602–3606 (1993).
Gage, F. H. et al. Proc. Natl Acad. Sci. USA 92, 11879–11883 (1995).
Suhonen, J., Ray, J., Blömer, U. & Gage, F. H. Curr. Protoc. Hum. Genet. 11, 13.3.1–13.3.24 (1996).
Kuhn, H. G., Dickinson-Anson, H. & Gage, F. H. J. Neurosci. 16, 2027–2033 (1996).
Kempermann, G., Kuhn, H. G. & Gage, F. H. Proc. Natl Acad. Sci. USA 94, 10409–10414 (1997).
Kempermann, G., Kuhn, H. G. & Gage, F. H. Nature 386, 493–495 (1997).
Ernst, A. et al. Cell 156, 1072–1083 (2014).
Spalding, K. L. et al. Cell 153, 1219–1227 (2013).
van Praag, H. et al. Nature 415, 1030–1034 (2002).
Gonçalves, J. T., Schafer, S. T. & Gage, F. H. Cell 167, 897–914 (2016).
Tosoni, G. et al. Neuron 111, 1714–1731 (2023).
Acknowledgements
F.H.G. thanks M. L. Gage, B. Coyne and S. Parylak for editorial input. This work was supported by NIH Grant #MH114030 (F.H.G.), American Heart Association/Paul G. Allen Frontiers Group Brain Health & Cognitive Impairment Initiative (19PABHI34610000), the Dolby Family and the Brinson Foundation.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing interests.
Rights and permissions
About this article
Cite this article
Gage, F.H. New neurons are born in the adult human brain. Nat Med 31, 356–357 (2025). https://doi.org/10.1038/s41591-025-03497-x
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41591-025-03497-x