Extended Data Fig. 2: Estimated mean percent changes in body weight from randomization (week 0) and from baseline of the 4-week behavioral treatment run-in (week −4) to week 24.

a, Mean (±s.e.) percent changes in body weight as measured from randomization to week 24 in the 76 early nonresponders randomized to behavioral treatment (BT) plus anti-obesity medication (AOM, phentermine = 15.0 mg d⁻¹) or BT plus placebo, as well as changes in the 55 early responders who were not randomized. b, Mean (±s.e.) percent changes in body weight as measured from baseline of the 4-week BT run-in in these same groups. Weight change values were estimated from linear mixed models.