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Cancer therapy

The innate power of natural killer cells in cancer therapy

A promising phase 1 trial with patients with refractory Hodgkin lymphoma underscores the potential value of allogeneic natural killer (NK) cell therapy guided by NK cell-specific engagers.

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Fig. 1: Study design and mechanism of action.

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Correspondence to Karl-Johan Malmberg.

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Competing interests

K.-J.M. has received research support from Oncopeptides for work related to immune engagers. All relationships have been approved by Oslo University Hospital, University of Oslo, Norway and Karolinska Institute, Stockholm, Sweden.

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Sohlberg, E., Malmberg, KJ. The innate power of natural killer cells in cancer therapy. Nat Med 31, 1755–1756 (2025). https://doi.org/10.1038/s41591-025-03712-9

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