Extended Data Fig. 1: Assessment of bias between 18S qRT-PCR- and TBS-based parasite densities. | Nature Medicine

Extended Data Fig. 1: Assessment of bias between 18S qRT-PCR- and TBS-based parasite densities.

From: Anti-sporozoite monoclonal antibody for malaria prevention: secondary efficacy outcome of a phase 2 randomized trial

Extended Data Fig. 1

A Bland-Altman plot demonstrates minimal bias (0.21 log10 parasites/mL) between log10 transformed Plasmodium 18S qRT-PCR- and TBS-based parasite densities. There was no density dependence to the bias (P = 0.19), as determined by simple linear regression with a two-sided P value. The solid black line represents the difference between log10 measurements (bias) and the dashed red lines represent mean bias ± 1 SD.

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