Extended Data Fig. 3: Relationship between enrollment date and time to clearance of baseline P. falciparum infection.

The y axis represents the number of days from enrollment (when the antimalarial drug AL was given) to the first qualitatively negative P. falciparum 18S qRT-PCR, shown by calendar date of enrollment (x axis). Among those who were infected at enrollment, clearance was defined as two consecutive negative 18S qRT-PCR results after enrollment. Each dot represents one participant. The 16 participants who remained 18S qRT-PCR positive through study day 21 (28 – 36 days after enrollment) are shown in shades of red. Participants who were uninfected at enrollment are shown in shades of gray/black (n = 196), and those who were infected at enrollment and cleared infections by study day 21 are shown in shades of blue (n = 118). Diamonds (n = 12) represent participants who were censored (that is participants who were still infected with P. falciparum when the last recorded study visit occurred).