Extended Data Fig. 5: Ligand interaction diagram of ceramide synthase.

2D ligand interaction diagram of: A C26:0 in the apo-state with Lag1, B C26:0 in the apo-state with Lac1, C C26:0 in the FB1-bound state with Lag1, D C26:0 in the FB1-bound state with Lac1, E FB1-binding to Lag1, F FB1-binding to Lac1, G PI16:0 binding to Lac1 in the apo-state and H PI16:0 binding to Lac1 in the FB1-bound state. I PI16:0 binding to Lip1 in FB1-bound state and Lip1* in J. Diagrams were calculated and visualized with LigPlot+¹.