Extended Data Fig. 4: Local cryo-EM density map quality of apo and FB1-bound ceramide synthase.

Side-by-side comparison of selected residues and ligands within all cryo-EM density maps of A Lag1 B FB1 (Fumonisin-B1) C Lac1, D Lip1, E Lip1*, F C26:0-His255 (Lag1/Lac1) G PI16:0-lipid (phosphoinositide) and ammonium ion NH4 + , H PE18:0-lipid (phosphoethanolamine). Contouring levels set to 0.16.