Correction to: Scientific Reports https://doi.org/10.1038/s41598-022-15668-8, published online 09 July 2022
The original version of this Article contained errors, where a study participant was omitted in the mild COVID-19 experimental group for “bulk” analysis. As the result, in the Results, under ‘A clinical cohort to study early COVID-19 with mild or moderate symptoms’,
“Subjects with mild symptoms exhibited a mean score of 12.9 ± 2.1 and 12.2 ± 2.8 for total PBMC assays (bulk) and assays of individual PBMCs (single-cell assays), respectively, which corresponded to the World Health Organization (WHO) Ordinal 8-point scale 1 (OS1, ambulatory and with no limitation of activities).”
now reads:
“Subjects with mild symptoms exhibited a mean score of 12.8 ± 1.9 and 12.2 ± 2.8 for total PBMC assays (bulk) and assays of individual PBMCs (single-cell assays), respectively, which corresponded to the World Health Organization (WHO) Ordinal 8-point scale 1 (OS1, ambulatory and with no limitation of activities).”
In Table 1, in column ‘Mild disease’, the 'Number of subjects', 'Sex (male/female)' and ‘Max severity score (± SE)’ have been corrected. The correct and incorrect values are listed below.
Incorrect:
Characteristics | Mild disease |
---|---|
Number of subjects | 7 |
Sex (male/female) | 4/3 |
Max severity score (± SE) | 12.9 ± 2.1 |
Correct:
Characteristics | Mild disease |
---|---|
Number of subjects | 8 |
Sex (male/female) | 5/3 |
Max severity score (± SE) | 12.8 ± 1.9 |
Additionally, the same error occurred in Supplementary Information Figure S1 and Supplementary Table S1.
The original Supplementary Figure S1 and accompanying legend appear below.
(A) Symptom severity sums for the subjects profiled with bulk assays and (B) severity scores for each reported symptom for the subjects profiled with bulk assays. (C) Symptom severity sums for subjects profiled with single-cell assays and (D) severity scores for each reported symptom for the subjects profiled with single-cell assays. For both cohorts, the sum of severity scores for all reported symptoms are shown for close contacts (green), COVID-19 subjects with mild symptoms (blue), and with moderate symptoms (orange).
A new row has been added to Table S1. It now reads:
Group | Alias ID | Race | Ethnicity | Day of PBMC collection | PCR | Serology Test (IgG) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mild | 7085CA | White | Non-Hispanic | 0 | 7 | 14 | N‡ | N | N | N | N | P |
The original Article and Supplementary Information files have been corrected.
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Giroux, N.S., Ding, S., McClain, M.T. et al. Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion. Sci Rep 13, 6462 (2023). https://doi.org/10.1038/s41598-023-33323-8
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DOI: https://doi.org/10.1038/s41598-023-33323-8