Figure 5
The heterogeneity of CRC samples with different SRS. (a) The correlation of SRS with several known biological processes. Orange represents the positive correlation and blue represents the negative correlation. (b) The correlation of SRS with 7 critical steps in the cancer-immunity cycles. Orange represents the positive correlation and blue represents the negative correlation. (c) The relationship between SRS and immune score calculated by ESTIMATE algorithm. (d) The relationship between SRS and stromal score calculated by ESTIMATE algorithm. (e) Comparison of immune biomarker gene expression levels between low- and high-risk groups. (f) Enrichment of cancer-related hallmarks in CRC samples from the low-risk group. (g) Enrichment of cancer-related hallmarks in CRC samples from the high-risk group. (h) The differences in the infiltration of immune cells between the low- and high-risk groups.
