Fig. 5

Immune-related analysis based on TCGA dataset: immune checkpoints (A), immune infiltration (B), the correlation between stemness index and GREM1 expression (C), the GREM1 expression between the low- and high-GREM1 groups (D), the correlation between TIDE score and GREM1 expression (E), the TIDE score between the low- and high-GREM1 groups (F), the GREM1 expression between the patients with or without response to immunotherapy (G), the number of the patients with or without response to immunotherapy between the low- and high-GREM1 groups (H). The IC50 of chemotherapy between the low- and high-GREM1 groups (I). mRNAsi: stemness index, IC50: half-maximal inhibitory concentration. ns, P ≥ 0.05; *, P < 0.05; **, P < 0.01; ***, P < 0.001.