Fig. 1 | Scientific Reports

Fig. 1

From: Quantitative detection of macular microvascular abnormalities identified by optical coherence tomography angiography in different hematological diseases

Fig. 1

Overview of the study. (A) Subject Enrollment: The diagnosis of blood diseases was based on the patients’ clinical manifestations and confirmed through blood and bone marrow data. (B) Data Collection: Subjects were categorized into different groups based on their diagnoses and laboratory disease indicators. Each patient and healthy control underwent a comprehensive ophthalmic examination using slit-lamp and Optical Coherence Tomography Angiography (OCTA). Parameters including Linear Vessel Density (LVD), Perfusion Vessel Density (PVD), and Foveal Avascular Zone (FAZ) were recorded for subsequent analysis. (C) Diagram of blood cell composition, a, normal erythrocyte; b, sickle-shaped erythrocyte; c, Normal leukocyte; d, Normal lymphocyte; e, abnormal lymphocytes. The cell body is larger than normal lymphocytes, the chromatin may be darker, and sometimes vacuoles may appear; f, normal platelets; g, deformation of platelets. OCTA, optical coherence tomography angiography; LVD, linear vessel density; PVD, perfusion vessel density. FAZ, foveal avascular zone.

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