Table 1 Susceptibility of Enterobacter chuandaensis strain 5885 and transconjugant 5885-J53.

From: First documentation of a clinical multidrug-resistant Enterobacter chuandaensis ST2493 isolate co-harboring blaNDM-1 and two blaKPC-2 bearing plasmids

Antimicrobials

MIC values (mg/L)

 

FAHZZU5885

FAHZZU5885-J53

E. coli J53

ATCC 25922

Aztreonam

>128 (R)

0.125 (S)

0.06 (S)

0.125 (S)

Imipenem

32 (R)

4 (R)

0.25 (S)

0.125 (S)

Meropenem

32 (R)

4 (R)

0.03 (S)

0.015 (S)

Ceftriaxone

128 (R)

32 (R)

0.06 (S)

0.06 (S)

Cefotaxime

>128 (R)

64 (R)

0.125 (S)

0.125 (S)

Ceftazidime

>128 (R)

>128 (R)

0.25 (S)

0.25 (S)

Levofloxacin

64 (R)

0.06 (S)

0.06 (S)

0.06 (S)

Ciprofloxacin

64 (R)

≤0.04 (S)

0.008 (S)

≤0.04 (S)

Amikacin

4 (S)

0.5 (S)

1 (S)

2 (S)

Gentamicin

128 (R)

1 (S)

1 (S)

1 (S)

Piperacillin/Tazobactam

>128/4 (R)

32/4 (R)

4/4 (S)

4/4 (S)

Fosfomycin

512 (R)

0.5 (S)

1 (S)

0.5 (S)

Chloramphenicol

>128 (R)

8 (S)

8 (S)

8 (S)

Trimethoprim/Sulfamethoxazole

8/156 (R)

0.125/2.375 (S)

0.125/2.375 (S)

0.125/2.375 (S)

Amoxicillin-Clavulanic acid

>128/64 (R)

>128/64 (R)

8/4 (S)

8/4 (S)

Cefepime

32 (R)

8 (SDD)

0.06 (S)

0.06 (S)

Ceftazidime-Avibactam

≥64/4 (R)

4/4 (S)

0.25/4 (S)

0.25/4 (S)

Tigecycline

1 (S)

0.125 (S)

0.125 (S)

0.06 (S)

Colistin

1 (S)

1 (S)

1 (S)

1 (S)

Omadacycline

16 (R)

1 (S)

0.5 (S)

0.5 (S)

Eravacycline

1a

≤0.06 (S)

≤0.06 (S)

≤0.06 (S)

Tetracycline

>128 (R)

2 (S)

2 (S)

1 (S)

  1. R, resistant; S, susceptible; I, intermediate.
  2. a FDA only interprets ≤ 0.05 as susceptible.
  3. SDD, susceptible-dose dependent.