Fig. 5

Promoter methylation levels of ACER1 in HNSCC. Box-whisker plots show ACER1 promoter methylation levels in patients with different subtypes of HNSCC, stratified according to (A) sample type, (B) individual cancer stage, (C) tumor grade, (D) node metastasis status, (E) patient gender, (F) tobacco smoking history, (G) TP53 mutation, (H) race and (I) age. * p < 0.05, ** p < 0.01, *** p < 0.001.