Fig. 7 | Scientific Reports

Fig. 7

From: Identification of ETV5 as a prognostic marker related to epigenetic modification in pan-cancer and facilitates tumor progression in hepatocellular carcinoma

Fig. 7

Relationship between ETV5 expression level and drug sensitivity in cancer. (A) Correlation between 8 drugs sensitivity and the expression level of ETV5 in pan-cancer cells based on the CellMiner database (P < 0.001). (B) Comparison of the sensitivity for the top 3 significantly related drugs in panel A between high and low ETV5 expression groups. (C) The scatterplot showed the distribution of drugs whose sensitivity was significantly correlated with the expression level of ETV5 (P < 0.05). (D, E) Comparison of the IC50 for antitumor drugs between high and low ETV5 expression groups in HCC cells based on the GDSC and CCLE databases, including oxaliplatin (D), gefitinib (E). (*P < 0.05, ***P < 0.001)

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