Fig. 8

Immune Landscape Analysis. (A) Utilizing the CIBERSORT algorithm, we identified notable differences in the immune cell composition between vitiligo patients and normal samples, with significant disparities observed in CD8 T cells (p = 0.008).(B) Pearson correlation analysis highlighted significant correlations between marker genes and specific immune cells: SNCA positively correlated with "mast cells resting" and negatively with “plasma cells”; IL33 and SLC1A4 showed negative correlations with "T cells CD4 naive" and "T cells regulatory (Treg)" respectively (*p < 0.05).