Table 4 Univariate and multivariate logistic regression models to determine risk factors for early recurrence.

From: Definition and risk factors for early recurrence in patients with laryngeal cancer after initial surgery

 

Univariate analysis

Multivariate analysis

 

OR

95%CI

P-value

OR

95%CI

P-value

Age

0.96

0.93-1.00

0.08

   

BMI(Kg/m)

1.06

0.95–1.18

0.31

   

Tobacco addiction (yes vs. no)

1.20

0.40–3.60

0.75

   

Alcohol addiction (yes vs. no)

1.32

0.60–2.90

0.49

   

Surgical approaches

  

0.48

  

0.65

Partial laryngectomy

Ref

Ref

Ref

Ref

Ref

Ref

Transoral laser surgery

0.58

0.21–1.58

0.28

0.76

0.22–2.67

0.67

Total laryngectomy

1.03

0.42–2.54

0.96

0.57

0.17–1.94

0.37

Subsites of tumor (glottic vs. the others)

0.77

0.32–1.83

0.55

0.82

0.26–2.58

0.82

Differentiation

Poor vs. moderate and well

2.51

0.87–7.24

0.09

2.47

0.65–9.43

0.19

Perineural invasion (yes vs. no)

3.07

1.14–8.25

0.026

2.30

0.72–7.41

0.16

Lymphovascular invasion (yes vs. no)

2.43

1.07–5.49

0.033

2.81

1.06–7.43

0.038

Adjuvant radiotherapy (no vs. yes)

2.40

1.06–5.44

0.036

3.12

1.04–9.39

0.043

TNM stage

1.53

1.04–2.27

0.032

1.96

1.05–3.66

0.035

Positive surgical margins (yes vs. no)

3.46

1.39–8.58

0.008

3.03

1.02–8.98

0.045

Lymph node metastasis (yes vs. no)

1.62

0.66–3.96

0.29

1.36

0.39–4.72

0.63

  1. OR = odds ratio; CI: confidence interval; BMI = body mass index, Ref = reference; TNM = tumor, node, metastasis.