Fig. 2 | Scientific Reports

Fig. 2

From: OM85 ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting Notch expression and modulating the IFN-γ/IL-4 ratio

Fig. 2

shows survival curves throughout the study. Initially, 12 mice were placed in both NaCl-PBS and NaCl-OM85 groups, with two from each group dying due to anesthesia and suffocation. In the BLM-NaCl and BLM-OM85 groups, BLM toxicity further increased mortality. The BLM-NaCl group started with 28 mice, decreasing to 14 by day 42, and then to 10 by tissue collection. The BLM-OM85 group started with 20 mice, with 10 surviving to day 42, all of whom made it to tissue collection. Kaplan–Meier survival analysis in GraphPad Prism 9.5 indicated significance levels: *P < 0.05, **P < 0.01, and ns for P > 0.05.

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