Fig. 2
Exome sequencing statistics and detection of artifactual base changes in somatic single nucleotide variant (SNV) calls in nine pediatric brain caner samples in current (Twist) and previous (Agilent) studies. (a) Distribution of depth of coverage. (b) Estimated fold 80 base penalties. (c) Median insert size calculated from uniquely aligned properly paired reads (mapping quality ≥ 20). (d) Distribution of insert size of uniquely aligned properly paired reads (mapping quality ≥ 20). (e) Number of primarily-called and SOBDetector-filtered autosomal SNV calls (dpeth ≥ 10). (f) Number of primarily-called and filtered autosomal SNV calls in context of SNV type (dpeth ≥ 10).
