Fig. 8 | Scientific Reports

Fig. 8

From: Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling

Fig. 8Fig. 8

Overexpression of ndufb10 ameliorated Ang II-induced mitochondrial dysfunction and apoptosis. (A) Representative mitochondrial mPTP opening and its quantitative analysis, n = 3. (B) Mitochondrial membrane potential and its quantitative analysis, n = 3. (C) Expression level of ndufb10 mRNA. n = 3. (D) TUNEL assay of apoptosis in H9C2 cells. Quantification of TUNEL-positive nuclei, n = 3. (E) Expression levels of apoptosis-related proteins, n = 3, Chemiluminescence signals were visualized and cropped using Protein Simple Compass software, original blots/gels are presented in Supplementary 2 Fig. 24–25. The whole cell lysates were used for western blot. The data are presented as the mean ± SEM; *P < 0.05; **P < 0.01.

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